Cost of Brand-Name Antiseizure Meds Increased Since 2010

WEDNESDAY, June 15, 2022 — The cost of brand-name antiseizure medications (ASMs) has increased since 2010, according to a study published online June 15 in Neurology.

Samuel Waller Terman, M.D., from the University of Michigan in Ann Arbor, and colleagues conducted a retrospective cohort study of beneficiaries with epilepsy in a 20 percent random Medicare sample with continuous Fee-for-Service coverage in 2008 to 2018.

The researchers found that in 2008, the most common ASM was phenytoin, which shifted to levetiracetam in 2018. From 2008 to 2018, brand-name, first-generation, and enzyme-inducing ASMs all decreased as a proportion of pill days (56 to 14 percent, 55 to 32 percent, and 44 to 24 percent, respectively). There was an initial decrease seen in the number of brand-name pill days per person-year from 2008 to 2010, which then plateaued given a notable increase in lacosamide pill days per person. From 2008 to 2010, there was a decrease observed in total brand-name costs per year, followed by an increase after 2010 ($150 million, $72 million, and $256 million in 2008, 2010, and 2018, respectively). Brand-name ASMs represented 79 percent of costs in 2018, despite accounting for only 14 percent of pill days; over time, a one-year pill supply became 277 percent more expensive for brand-name drugs and 42 percent less expensive for generic medications. Compared with their generic equivalents, many brand-name ASMs cost about 10-fold more per pill day.

“Doctors should consider the societal cost when judging whether the increased expense of brand-name drugs is worth the possible benefits,” Terman said in a statement.

Abstract/Full Text (subscription or payment may be required)

Editorial (subscription or payment may be required)

© 2022 HealthDay. All rights reserved.

Source link

Published by Drugs.Com Know More. Be Sure
Managed by Pharma Enthusiast, To claim this account, mail us at
Get Connected!
Come and join Pharma Community. Expand your network in Pharma!


No comments yet